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Two Vitamins That All Diabetics Should Know About Type II diabetes is one of the most prevalent diseases
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in the world today. The original GAIT study results in 2006 found the supplements did not reduce the pain of knee arthritis, except among a small group of patients with moderate to severe pain. “At two years, no treatment sho what we determined to be a clinically important reduction in joint
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space width loss,” said Dr. The trial is called glucosamine/chondroitin arthritis intervention trial or GAIT. Wendel - Two hugely popular supplements used to fight arthritis and joint pain, glucosamine and chondroitin sulfate, do not seem to work any better than placebo to slow the loss of knee cartilage
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in osteoarthritis, researchers reported on Monday. Writing in the October issue of Arthritis & Rheumatism, Sawitzke and colleagues said
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they had trouble interpreting their results because patients who took placebos had a smaller loss of cartilage than they should have. That’s good, because the stakes are high.
Now
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there may be another step you can take to protect your body from the ravages of this disease. The participants
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were divided into two groups, and assigned to take either 1,250 mg of vitamin C and 680 IU of vitamin E (d-alpha-tocopherol) each morning, or five matching placebo
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tablets. In both phase I and phase II, urinary albumin excretion rates decreased significantly in the patients taking the vitamins (an average of 19%).
The GAIT researchers continued to watch 572 volunteers for another 18 months and found the supplements did not appear to slow the loss of cartilage, taken either alone or together. (It can also be a sign of complications from hypertension and other manifestations
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of cardiovascular
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disease, another com diabetic complication.) Unfortunately, mainstream medicine hasn’t yet found a treatment approach that consistently reduces this important marker. Maurice Katz, director of the NIH’s National Institute of Arthritis and Musculoskeletal and Skin Diseases.. But a new study suggests that vitamin supplementation may help prevent some of these problems, by addressing a known marker for these serious complications. Fortunately, it is also one of the
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most treatable.
And none of the participants reported any side effects from the treatment. In this Danish
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study, researchers tracked the effect of vitamins C and E on the urinary albumin excretion rate (AER) of patients with Type II diabetes. The study, funded by the National Center for Complementary and Alternative Medicine at the National Institutes
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of Health, confirms other findings showing the supplements have few or no effects. If you have Type II diabetes, chances are you’re already keeping a close watch on your health. (AER can be reported in several different ways, but in this study they defined high levels as anywhere from 30 to 300 milligrams of albumin in 24 hour urine collection sample.) All but
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one of the participants were taking ACE inhibitors before they entered the study;
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glucophage vitamin b12 they were all required to stop taking ACE inhibitors and/or vitamin supplements eight weeks before the study began. But, according to the new study in the journal Diabetic Medicine, they
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don’t work for the majority of people.
Albumin is a protein synthesised in the liver that works
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to transport various substances in the blood stream. The addition of these two basic nutrients to your regimen is a simple step that may give your body some added protection from the degenerative effects of Type II diabetes. “Research continues to reveal that osteoarthritis, the most com form of arthritis, appears to be the result of an array
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of factors including
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age, gender, genetics, obesity, and joint injuries,” said Dr. So they recruited 29 participants (20 men and 9 women) and set out to track the vitamins effects on humans.
But the researchers said some of their findings were confusing and said more study was needed. The participants’ average age was 58, and, on average, they had had Type II diabetes for 12 years. This continued for four weeks; then
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the participants began a three-week washout period, and then “crossed over.” (This means that the participants in the first placebo group then took
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vitamins C and E, and the participants that first took the vitamins then took placebo.) This continued for another four weeks. Vitamins C and E had shown kidney-protective effects in animal studies.
With vitamin health effects weight loss, a healthy diet, and exercise, many people with Type II diabetes are able
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to maintain healthy blood sugar levels without medication.
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Angiotensin converting enzyme (ACE) inhibiting drugs, which are used to lower blood pressure, have also been shown to lower the AER of some patients with Type II diabetes. They said arthritis worsened in 24 percent of participants taking both, similar to those taking placebo.
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Type II diabetes can lead to a variety of serious health problems, like kidney disease and cardiovascular disease. When too much albumin is excreted in the urine, it’s a strong sign that the kidneys are in trouble. Nefen Sawitzke of the University of Utah School of Medicine, who helped lead the study.